High-level expression of the FtsA protein inhibits cell septation in Escherichia coli K-12
Open Access
- 1 August 1990
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 172 (8) , 4736-4740
- https://doi.org/10.1128/jb.172.8.4736-4740.1990
Abstract
DNA fragments encoding the ftsA gene were subcloned into plasmids downstream of a lac promoter or a tac promoter. These plasmid constructs, when transformed into wild-type and mutant strains, inhibited normal cell septation, causing the formation of long nonseptate filaments. This phenotype is due to overproduction of the FtsA protein.This publication has 33 references indexed in Scilit:
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