Micropunctate fluorescein staining of the human corneal surface: microerosions or cystic spaces?

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Abstract
Purpose: To study in vivo the phenomenon of micropunctate fluorescein staining of the human corneal surface.Methods: Patients were examined in the slit‐lamp and photographed by the means of photomicrography. The staining pattern of fluorescein was compared with that of superimposed rose bengal staining.Results: The staining patterns showed a great correspondence.Conclusion: The findings indicate that micropunctate fluorescein staining probably reveals disruptions of intercellular junctions permitting penetration and accumulation of stained fluid beneath diseased cells in situ.