Preferential Induction of Rough Variants in Streptococcus mutans by Ethidium Bromide
- 1 September 1973
- journal article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 52 (5) , 1070-1075
- https://doi.org/10.1177/00220345730520051401
Abstract
Different colonial variants of Streptococcus mutans were studied. Rough variants were induced frequently from an original mucoid-type strain in cultures to which ethidium bromide was added. Rough variants had less insoluble dextran like polysaccharides than the original mucoid strain. Mitomycin C caused cell lysis in mucoid cells but not in rough cells.Keywords
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