Cell-permeable GPNA with appropriate backbone stereochemistry and spacing binds sequence-specifically to RNA

2 December 2004

journal article
Published by Royal Society of Chemistry (RSC) in Chemical Communications

No. 2,p. 244-246
https://doi.org/10.1039/b412522c

Abstract

Guanidine-based peptide nucleic acid (GPNA) with a D-backbone configuration and alternate spacing binds sequence-specifically to RNA and is readily taken up by both human somatic and embryonic stem (ES) cells.

Keywords

SOMATIC
GPNA
BACKBONE
GUANIDINE
STEREOCHEMISTRY
CONFIGURATION
READILY
PERMEABLE
TAKEN

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