Reproduction of Toxoplasma gondii by Internal Budding

Abstract
T. gondii from peritoneal exudate of infected mice was studied in smears stained with silver protein. Photographs and drawings are presented to show that, in such material, this species reproduces by a hitherto undescribed method of internal budding which is named by the authors "endodyogeny". In this process, each parent cell produces 2 daughter cells which develop internally. Upon reaching full growth, the joined daughter cells are freed of the parent, destroying the latter in the process. Final separation of daughter cells than takes place. Out of 1298 organisms counted on 3 different smears, 14% were in some state of division.
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