Estrogen Antagonisms: Effects of Gluco- and Mineralocorticoids on Estrone-Induced Uterine Growth.
- 1 February 1960
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 103 (2) , 294-296
- https://doi.org/10.3181/00379727-103-25493
Abstract
Uterine growth in intact, immature mice was stimulated by injection of 0.3 [mu]g of estrone. When administered simultaneously, neither cortisone acetate nor cortisol acetate had any evident inhibitory effect. Deoxycortone (DCA) was a definite estrone antagonist. A preliminary test with aldosterone suggested that it too was active. The mineralocorticoids appeared to be of equal potency, about 10% progesterone.Keywords
This publication has 1 reference indexed in Scilit:
- THE MODIFICATION OF ESTROGEN-INDUCED CHANGES IN RAT VAGINAS WITH STEROIDS AND RELATED AGENTSAnnals of the New York Academy of Sciences, 1959