Amphetamine, Haloperidol, and Experience Interact to Affect Rate of Recovery After Motor Cortex Injury
- 27 August 1982
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 217 (4562) , 855-857
- https://doi.org/10.1126/science.7100929
Abstract
Rats subjected to unilateral ablation of the motor cortex and placed on a narrow beam displayed transient contralateral paresis. An immediate and enduring acceleration of recovery was produced by a single dose ofd-amphetamine given 24 hours after injury. This effect was blocked by haloperidol or by restraining the animals for 8 hours beginning immediately after amphetamine administration. A single dose of haloperidol given 24 hours after injury markedly slowed recovery. This effect was also blocked by restraining the animals.This publication has 24 references indexed in Scilit:
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