The Thrombogram: Monitoring Thrombin Generation in Platelet Rich Plasma
- 1 January 2000
- journal article
- editorial
- Published by Georg Thieme Verlag KG in Thrombosis and Haemostasis
- Vol. 83 (04) , 589-591
- https://doi.org/10.1055/s-0037-1613868
Abstract
Summary: A method is described in which thrombin activity in clotting plasma can be monitored through the continuous measurement of the fluorescent split-product of the substrate Z-Gly-Gly-Arg-AMC. The signal is not impaired by turbidity; therefore proper measurement is not disturbed by the occurrence of a clot or the presence of platelets and direct measurement in platelet rich plasma is possible.Keywords
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