Induction of nucleolar segregation in adrenal fasciculata cells by actinomycin D
- 1 March 1980
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 36 (3) , 345-346
- https://doi.org/10.1007/bf01952317
Abstract
Actinomycin D administration to young rats provokes segregation of the nucleoli of adrenal fasciculata cells into 5 distinct zones (granular, fibrillar and vacuolar zones, a fibrillar center, and a dense fibrillar or “contrasted” zone); in the cytoplasm, there were dilations of Golgi cisternae. In spite of the nucleolar segregation, the cytoplasmic alterations suggest the maintenance of protein synthesis.Keywords
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