Gene with Quantitative Effect on Circulating Interferon Induced by Newcastle Disease Virus
- 1 May 1969
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 3 (5) , 506-12
- https://doi.org/10.1128/jvi.3.5.506-512.1969
Abstract
Circulating interferon production, induced by Newcastle disease virus, is about seven times higher in C 57 Black mice than i Balb/c/Gif mice. A Mendelian analysis was carried out and circulating interferon production was measured in reciprocal F 1 hybrids, in the F 2 generation, in progeny of backcrosses of F 1 hybrids to either parent strain, and in second backcross progeny. The results indicate that a single, partly dominant, autosomal factor is responsible for the difference in circulating interferon production between both parent strains.Keywords
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