High-Dose Intravenous ?-Immunoglobulin Infusion in the Treatment of Thrombotic Thrombocytopenic Purpura

Abstract
† Thrombotic thrombocytopenic purpura has been treated with plasmapheresis, exchange transfusion, splenectomy, antiplatelet compounds, glucocorticoids, and vincristine sulfate infusion. We describe a patient with thrombotic thrombocytopenic purpura who has failed on treatment with plasmapheresis, antiplatelet compounds, glucocorticoids, and vincristine, was successfully treated with high-dose γ-immunoglobulin infusion, and has been maintained in prolonged remission without further immunoglobulin infusion for more than 14 months at the time of this report. (Arch Intern Med 1987;147:2165-2167)