URINARY RETENTION DURING I.M. AND EXTRADURAL MORPHINE ANALGESIA

Open Access
Publisher Website
Google Scholar
Abstract
In the postoperative period fifty-six healthy patients undergoing cholecystectomy or operations for duodenal ulcer, received, in a randomized order, i.m , “high-level” or “low-level” extradural morphine Thirty-five per cent in the i m. group, 33% in the high-level group and 50% in the low-level group suffered urinary retention, in all cases within the first 24 h The mean cumulative dose of morphine necessary for pain relief was m the same range (13 4–16 5 mg) during the first 2 h of therapy for all groups, while the amounts after 24 and 48 h were twice to four times with the i m route compared with the extradural route. A peripheral effect of morphine on the urinary bladder is possible and the mechanism of action is discussed