Effect of Vitamin E and CCL4 on Fat, Respiration and Choline Oxidase of Rat Livers.
- 1 December 1951
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 78 (3) , 858-861
- https://doi.org/10.3181/00379727-78-19242
Abstract
A deficiency of vit. E in a 10% casein diet lowered the liver fat of young rats from 12.7% to 8.7% on the dry basis. Following CCI4 poisoning the extent and course of fatty changes in the liver was not influenced by vit. E, although this upplement lessened the growth depression during 8 wks. on chronic CCI4 treatment. The O2 uptake by liver slices in glucose-Ringers increased 100% within 24 hrs. after CCl4 injns. into rats without dietary vit. E, but increased only about 30% when rats received this factor. Supplements of vit. B12 did not influence respiration rates. The choline oxidase of rat liver was not influenced by either vit. E or CC14.Keywords
This publication has 4 references indexed in Scilit:
- Effect of Vitamins E, B12 and Folacin on CCL4 Toxicity and Protein Utilization in Rats.Experimental Biology and Medicine, 1951
- A fatal Vitamin E Deficiency Disease in Rats Characterized by Massive Lung Hemorrhage and Liver NecrosisJournal of Nutrition, 1949
- Protective Effect of Vitamin B12 Upon Hepatic Injury Produced by Carbon Tetrachloride.Experimental Biology and Medicine, 1949
- INTERRELATION BETWEEN ALPHA-TOCOPHEROL AND PROTEIN METABOLISM .3. THE PROTECTIVE EFFECT OF VITAMIN-E AND CERTAIN NITROGENOUS COMPOUNDS AGAINST CCL4 POISONING IN RATS1948