Biosynthesis of riboflavine in Saccharomyces cerevisiae: the role of genes rib 1 and rib 7 .
- 1 June 1972
- journal article
- Vol. 110 (3) , 818-22
Abstract
Haploid strains of Saccharomyces cerevisiae with mutations in two different rib genes were constructed. These strains were studied by tetrad analysis and by quantitative determination of accumulation products. The genes rib(1), rib(7), and rib(2) are not linked to each other. rib(1)-rib(7) strains and rib(1)-rib(2) strains exhibit the phenotypic properties of rib(1) strains. rib(7)-rib(2) strains show the phenotypic properties of rib(7) strains. The results support the conclusion that the genes rib(1) and rib(7) code for the first and second enzyme of the riboflavine pathway, respectively.This publication has 10 references indexed in Scilit:
- Biosynthesis of riboflavin. Formation of 6-hydroxy-2,4,5-triaminopyrimidine in rib 7 mutants of Saccharomyces cerevisiae.1971
- Biosynthesis of riboflavin. Formation of 2,5-diamino-6-hydroxy-4-(1'-D-ribitylamino)pyrimidine in a riboflavin auxotroph.1970
- Stereospecificity of the enzymic synthesis of the o-xylene ring of riboflavinJournal of the American Chemical Society, 1970
- Mechanism of elimination of protons from the methyl groups of 6,7-dimethyl-8-ribityllumazine by riboflavine synthetaseBiochemistry, 1970
- Biosynthesis of riboflavin. Mutants accumulating 6‐hydroxy‐2,4,5‐triaminopyrimidineFEBS Letters, 1969
- Biochemical and genetic classification of riboflavine deficient mutants of Saccharomyces cerevisiaeMolecular Genetics and Genomics, 1969
- UBER ZWISCHENPRODUKTE DER RIBOFLAVIN-BIOSYNTHESE BEI SACCHAROMYCES CEREVISIAE1967
- Application of Chromatography. XXXII. Biosynthesis of Riboflavin by Eremothecium ashbyii.Pharmaceutical Bulletin, 1957