The Absolute Configurations of the α- and β-Methylcholine Isomers and Their Acetyl and Succinyl Esters
- 1 September 1963
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 15 (1) , 349-361
- https://doi.org/10.1111/j.2042-7158.1963.tb12798.x
Abstract
The absolute configurations of the (+)-acetyl-α- and -β-methyl-choline iodides have been established, being related to D(−)-alanine hydrochloride and L(+)-lactic acid respectively. The (+)-, (−)- and racemic forms of the precursor amino-alcohols have been converted to the succinyl esters and these quaternised.Keywords
This publication has 14 references indexed in Scilit:
- Muscarinic ReceptorsNature, 1961
- Über Muscarin. 7. Mitteilung. Synthese und absolute Konfiguration des MuscarinsHelvetica Chimica Acta, 1957
- Substances curarisantes dérivées de la cholineBulletin des Sociétés Chimiques Belges, 1952
- 272. N-substituted amino-acids. Part I. A new method of preparation of dimethylamino-acidsJournal of the Chemical Society, 1950
- Preparation and Properties of Acetyl Dextro-and Acetyl Levo-β-methylcholine ChlorideJournal of the American Chemical Society, 1935
- Die Konflguration des Alanins. (4. Mitteilung über sterische Reihen)Berichte der deutschen chemischen Gesellschaft (A and B Series), 1924
- Über proteïnogene Amino‐Alkohole und Choline IIHelvetica Chimica Acta, 1922
- Bildung aktiver, sekundärer Aminosäuren aus Halogensäuren und primären AminenEuropean Journal of Inorganic Chemistry, 1916
- XCVI.—The resolution of benzoylalanine into its optically active componentsJournal of the Chemical Society, Transactions, 1912
- LXXXVI.—Resolution of lactic acid into its optically active componentsJournal of the Chemical Society, Transactions, 1893