Design and synthesis of statine-Containing BACE inhibitors
- 6 November 2003
- journal article
- research article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 13 (24) , 4335-4339
- https://doi.org/10.1016/j.bmcl.2003.09.037
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- Aβ Modulation: The Next Generation of AD TherapeuticsAnnals of the New York Academy of Sciences, 2006
- Design and Synthesis of Statine-Based Cell-Permeable Peptidomimetic Inhibitors of Human β-SecretaseJournal of Medicinal Chemistry, 2003
- The Search for γ-Secretase and Development of InhibitorsCurrent Medicinal Chemistry, 2002
- Inhibition of BACE, a promising approach to Alzheimer's disease therapy.Current Topics in Medicinal Chemistry, 2002
- Secretase Targets for Alzheimer's Disease: Identification and Therapeutic PotentialJournal of Medicinal Chemistry, 2001
- Toward a Comprehensive Theory for Alzheimer's Disease. Hypothesis: Alzheimer's Disease Is Caused by the Cerebral Accumulation and Cytotoxicity of Amyloid β‐ProteinAnnals of the New York Academy of Sciences, 2000
- In search of an enzyme: the β-secretase of Alzheimer's disease is an aspartic proteinaseTrends in Neurosciences, 2000
- Human aspartic protease memapsin 2 cleaves the β-secretase site of β-amyloid precursor proteinProceedings of the National Academy of Sciences, 2000
- Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activityNature, 1999
- β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACEScience, 1999