Topical negative pressure in wound management

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Abstract
Objective To investigate the role of topical negative pressure (TNP) therapy in the management of difficult wounds. Design Prospective consecutive patient series. Patients and setting 30 patients referred to our tertiary plastic and reconstructive surgical service with wounds deemed unsuitable for reconstructive surgery were treated between November 1997 and the end of December 1998. The mean pretreatment duration of the wounds was 418 days (range, 8‐1650 days). All wounds were at least Grade Ill pressure sores. Intervention Topical negative presssure therapy (TNP) using the VAC device (KCI Medical, San Antonio, USA). Suction (75‐125mmHg) was continuous for the first 48 hours, then intermittent (2 min on, 5 min off). Main outcome measures Achievement of wound healing endpoints: (1) complete healing of the wound; (2) obliteration of the wound cavity to allow surface dressings; or (3) closure of the wound by suture or skin graft. Results TNP was successful in 26 out of 30 patients with mean therapy time of 35 days (range, 3‐124 days). Healing was more rapid in acute (less than six weeks old) wounds. A reduction in the number of bacterial species and colonies was also observed during therapy. Conclusion TNP can, in some circumstances, promote rapid secondary wound healing. A further randomised trial of TNP versus more traditional wound management modalities is justified.