A Potential Regulatory Polymorphism Upstream of hairy Is Not Associated With Bristle Number Variation in Wild-Caught DrosophilaSequence data from this article have been deposited with the EMBL/GenBank Data Libraries under accession nos. AY587211, AY587212, AY587213, AY587214, AY587215, AY587216, AY587217, AY587218, AY587219, AY587220, AY587221, AY587222, AY587223, AY587224, AY587225, AY587226.
- 1 August 2004
- journal article
- Published by Oxford University Press (OUP) in Genetics
- Vol. 167 (4) , 2127-2131
- https://doi.org/10.1534/genetics.104.026732
Abstract
To extend results from laboratory genetic mapping experiments to natural populations it is necessary to estimate the phenotypic effects attributable to laboratory-identified genetic factors in nature. We retested a polymorphism found to be strongly associated with an increase of 0.35 sternopleural bristles in laboratory strains in two large samples of wild-caught Drosophila melanogaster. Despite >90% power to detect effects as low as 0.27 bristles (<1% of the total variation in bristle number) we did not replicate the association in nature. Potential explanations for this result are explored.Keywords
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