High Incidence of Spontaneous Cervical and Vaginal Tumors in an Inbred Strain of Brown Norway Rats (BN/Bi)
- 1 September 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 57 (3) , 549-554
- https://doi.org/10.1093/jnci/57.3.549
Abstract
The incidence of spontaneously occurring tumors of the cervix and vagina was unusually high in an inbred strain of Brown Norway rats (BN/Bi). Fifty-four tumors were diagnosed in the cervixes or vaginas of 252 rats. Of the tumors, 7 were squamous cell carcinomas, 4 were leiomyomas, and the rest were sarcomas. These tumors were found in nearly 20% of all female rats that died naturally.Keywords
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