Intraocular Pressure and Its Response to Topical Corticosteroids in Diabetes

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Abstract
A high prevalence of elevated intraocular pressures in the diabetic population is less striking in those with proliferative diabetic retinopathy than in those without proliferative changes. In both adult and juvenile groups without proliferative retinopathy, there is a significantly higher prevalence of elevated intraocular pressure after application of topical corticosteroids than in the nondiabetic population. In contrast, the distribution of corticosteroid response in the group of diabetics with proliferative retinopathy resembles more closely that in the nondiabetic volunteer population and differs significantly from that in diabetics without proliferative changes. Speculations concerning the relationship of intraocular pressure and corticosteroid responsiveness to the development of proliferative diabetic retinopathy are presented.