Serum Amphotericin-B Assay by Scanning Spectrophotometer
- 1 December 1988
- journal article
- research article
- Published by Wolters Kluwer Health in Therapeutic Drug Monitoring
- Vol. 10 (4) , 486-489
- https://doi.org/10.1097/00007691-198804000-00020
Abstract
We describe a simple, specific, 3-min assay for amphotericin-B in serum based on the absorbance at 408 nm and spectral scanning between 450 and 350 nm of the drug in acetonitrile extracts. The method correlated well with a high-performance liquid chromatographic method.This publication has 1 reference indexed in Scilit:
- Sensitive high-pressure liquid chromatographic assay for amphotericin B which incorporates an internal standardAntimicrobial Agents and Chemotherapy, 1986