SYSTEMIC LUPUS-ERYTHEMATOSUS WITH NEGATIVE LE CELLS AND ANTI-NUCLEAR FACTOR

  • 1 January 1978
    • journal article
    • research article
    • Vol. 5  (2) , 142-147
Abstract
In the course of a prospective study of 165 patients with SLE [systemic lupus erythematosus], a subgroup of 8 patients with active SLE yet with persistently negative tests for ANF [anti-nuclear factor] and LE [lupus erythematosus] cells was identified. These patients were characterized by a photosensitive skin rash, a negative lupus band test, a high incidence of arthritis, a mild form of renal disease and a positive family history for connective tissue disease. Antibodies to DNA and cytoplasmic antigens were detected in a few.

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