BIOLOGICAL ACTIVITIES OF PHTHALOCYANINES‐XL PHOTOTOXICITY OF SULFONATED ALUMINUM NAPHTHALOCYANINES TOWARDS V‐79 CHINESE HAMSTER CELLS
- 1 March 1990
- journal article
- research article
- Published by Wiley in Photochemistry and Photobiology
- Vol. 51 (3) , 313-317
- https://doi.org/10.1111/j.1751-1097.1990.tb01716.x
Abstract
The phototoxicity of sulfonated aluminum naphthalocyanines towards V-79 Chinese hamster cells is investigated. The disulfonated naphthalocyanine exhibits similar photostability, but better cell penetrating properties than the tetrasulfonated dyes. The capacity of the naphthalocyanines to generate singlet oxgyen is comparable to that of the corresponding phthalocyanines. However, in contrast to the phthalocyanine dyes, the sulfonated aluminum naphthalocyanines show very little phototoxicity towards the V-79 cells, suggesting close association with non-vital cell constituents or extensive formation of photoinactive adducts and aggregates.Keywords
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