AN AGGLUTININ IN THE HEMOLYMPH OF AN ASCIDIAN PROMOTING ADHESION OF SHEEP ERYTHROCYTES TO MOUSE MACROPHAGES

  • 1 January 1981
    • journal article
    • research article
    • Vol. 42  (4) , 661-669
Abstract
Sheep erythrocytes sensitized with subagglutinating doses of hemolymph from Botrylloides leachii bound strongly to mouse peritoneal macrophages in vitro. Erythrocytes sensitized with similar agglutinating doses of plant lectins or hemolymph from the fresh water crayfish Cherax destructor did not adhere. The adherence promoted by B. leachii hemolymph appears to be a heteroagglutination reaction mediated by a molecule which binds to lactose-like determinants on both erythrocytes and macrophages.