Metabolism of IgM in the tropical splenomegaly syndrome
- 1 January 1976
- journal article
- Published by Oxford University Press (OUP) in Transactions of the Royal Society of Tropical Medicine and Hygiene
- Vol. 70 (4) , 346-348
- https://doi.org/10.1016/0035-9203(76)90097-3
Abstract
IgM metabolism was studied in five patients with the tropical splenomegaly syndrome and in five controls. The half-life and turnover time of I 125 IgM was similar in the two groups. We conclude that the raised serum IgM levels found in patients with the tropical splenomegaly syndrome are not due to decreased IgM catabolism but are due to increased IgM production.Keywords
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