SWI/SNF: The crossroads where extracellular signaling pathways meet chromatin
- 9 September 2005
- journal article
- review article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 207 (2) , 309-314
- https://doi.org/10.1002/jcp.20514
Abstract
The coordinated expression of the genome in response to extracellular cues is ensured by enzymatic cascades signaling to the nucleus. These pathways generate chromatin modifications at specific loci controlling the transcription of signal‐dependent and tissue‐specific genes. The SWI/SNF chromatin remodeling complex offers the ideal surface for integrating these signals in the execution of diverse or even opposite biological programs. J. Cell. Physiol. 207: 309–314, 2006.Keywords
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