Fluorescent Modification of Adenosine 3′,5′-Monophosphate: Spectroscopic Properties and Activity in Enzyme Systems
- 21 July 1972
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 177 (4045) , 279-280
- https://doi.org/10.1126/science.177.4045.279
Abstract
The synthesis of a highly fluorescent analog of adenosine 3',5'-monophosphate, namely, 1,N6-ethenoadenosine 3',5'-monophosphate, has provided a powerful probe for systems involving adenosine 3',5'-monophosphate. The potential utility of this analog is indicated by its long fluorescent lifetime, detectability at low concentration, and relatively long wavelength of excitation (300 nanometers). In protein kinase systems it is a highly acceptable substitute for adenosine 3',5'-monophosphate.Keywords
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