Delayed Primary Closure. Tissue Gas Tensions in Healing Rat Skin Incisions

Abstract
Healing of delayed primary closure (DPC) wounds was investigated. With delays of 3-6 days DPC wounds developed higher late term mechanical strength than control primary closure (PC) wounds. Measurements of wound tissue gas tensions were performed with implanted silicone tonometer tubes. Higher p[partial pressure]O2 values were found in DPC wounds than in control PC wounds from 6-15th postoperative day. No difference in pCO2 was found between the 2 types of wounds. Results gave evidence of a higher local O2 supply in DPC wounds.