Thalamic atrophy following cerebral infarction in the territory of the middle cerebral artery.
- 1 May 1991
- journal article
- abstracts
- Published by Wolters Kluwer Health in Stroke
- Vol. 22 (5) , 615-618
- https://doi.org/10.1161/01.str.22.5.615
Abstract
We investigated shrinkage of the ipsilateral thalamus following infarction in the territory of the middle cerebral artery in 33 patients who were admitted less than or equal to 2 days after the stroke and who were followed by computed tomography for greater than 1 year with no recurrences. The thalamic area was measured on the computed tomograms, and the ratio of the ipsilateral area to the contralateral area was calculated. All values were compared with values from the initial computed tomogram taken less than or equal to 2 days after the stroke. The values of the ratio on follow-up computed tomograms decreased gradually in 15 patients. In these cases, the area of the ipsilateral thalamus was significantly reduced after 1 year (p less than 0.01) and marked atrophy was observed. These results demonstrate the significance of remote changes over a long period of time after focal cerebral infarction.Keywords
This publication has 8 references indexed in Scilit:
- Atrophy of the ipsilateral substantia nigra following middle cerebral artery occlusion in the ratBrain Research, 1990
- Thalamic infarctsNeurology, 1988
- Nonhemorrhagic infarction of the thalamusNeurology, 1984
- 2-Deoxyglucose uptake and histologic changes in rat thalamus after neocortical ablationsExperimental Neurology, 1984
- Delayed neuronal death in the gerbil hippocampus following ischemiaBrain Research, 1982
- Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery OcclusionJournal of Cerebral Blood Flow & Metabolism, 1981
- Thalamocortical synaptic relations: A review with emphasis on the projections of specific thalamic nuclei to the primary sensory areas of the neocortexBrain Research Reviews, 1979
- Death of the central neuron: An electron microscopic study of thalamic retrograde degeneration following cortical ablationJournal of Neurocytology, 1973