Primaquine-Induced Changes in Morphology of Exoerythrocytic Stages of Malaria
- 14 June 1968
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 160 (3833) , 1233-1234
- https://doi.org/10.1126/science.160.3833.1233
Abstract
Exposure to primaquine for 48 hours caused lesions in the exoerythrocytic stages of Plasmodium fallax grown in cultivated cells derived from embryonic turkey brain. The lesions appeared in the form of cytoplasmic vacuoles when viewed under the light microscope. The electron microscope revealed these vacuoles as swollen mitochondria readily identifiable by their typical protozoan cristae. Mitochondria of the host cell were unaffected.Keywords
This publication has 2 references indexed in Scilit:
- Procedures for maximum production of exoerythrocytic stages of Plasmodium fallax in tissue cultureExperimental Parasitology, 1966
- THE FINE STRUCTURE OF THE EXOERYTHROCYTIC STAGES OF PLASMODIUM FALLAX The Journal of cell biology, 1966