Abstract
The Journal this week carries an article indicating that clinically evident gallbladder disease is five or six times more common in a tribe of Indians living south of Phoenix, Arizona, than in the adult population of Framingham, Massachusetts "So what?" may be the reader's immediate reaction, but before he says it too loudly, perhaps he can be persuaded otherwise.Few approaches in recent years have proved as fruitful in elucidating the degenerative diseases of man as epidemiologic studies. This is the methodology that has linked smoking with chronic pulmonary disease, and dietary habits with atherosclerosis. Particularly productive have been studies . . .

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