Asymmetric Transfer Hydrogenation of Ketones with Bifunctional Transition Metal-Based Molecular Catalysts
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- 26 October 2007
- journal article
- review article
- Published by American Chemical Society (ACS) in Accounts of Chemical Research
- Vol. 40 (12) , 1300-1308
- https://doi.org/10.1021/ar700134q
Abstract
Recent development of conceptually new chiral bifunctional transition metal based catalysts for asymmetric reductive transformations is described. The chiral bifunctional molecular catalyst promoted reduction is now realized to be a powerful tool to access chiral compounds in organic synthetic procedures in both academia and industry. Based on structural investigation of the actual catalyst and its intermediates and a deep understanding of the reaction mechanism, this asymmetric reduction system can be widely used to produce valuable chiral alcohols and is now is applicable to commercial scale production.Keywords
This publication has 66 references indexed in Scilit:
- Bifunctional transition metal-based molecular catalysts for asymmetric synthesesOrganic & Biomolecular Chemistry, 2006
- Asymmetric Transfer Hydrogenation of Acetophenone with 1R,2S-Aminoindanol/Pentamethylcyclopentadienylrhodium CatalystOrganic Process Research & Development, 2004
- Asymmetric Transfer Hydrogenation of α-Aminoalkyl α‘-Chloromethyl Ketones with Chiral Rh ComplexesThe Journal of Organic Chemistry, 2004
- (β-Amino alcohol)(arene)ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation of Functionalized Ketones − Scope, Isolation of the Catalytic Intermediates, and Deactivation ProcessesEuropean Journal of Organic Chemistry, 2000
- Practical Synthesis of (S)-1-(3-Trifluoromethylphenyl)ethanol via Ruthenium(II)-catalyzed Asymmetric Transfer HydrogenationOrganic Process Research & Development, 2000
- Amino Alcohol Coordination in Ruthenium(II)-Catalysed Asymmetric Transfer Hydrogenation of KetonesEuropean Journal of Inorganic Chemistry, 1999
- Kinetic Resolution of Racemic Secondary Alcohols by RuII‐Catalyzed Hydrogen TransferAngewandte Chemie International Edition in English, 1997
- Asymmetric Transfer Hydrogenation Catalyzed by Chiral Ruthenium ComplexesAccounts of Chemical Research, 1997
- (Cyclopentadienone)ruthenium carbonyl complexes - a new class of homogeneous hydrogenation catalystsOrganometallics, 1985
- PARTIALLY ASYMMETRIC MEERWEIN-PONNDORF-VERLEY REDUCTIONSJournal of the American Chemical Society, 1950