The Effect of Long-Term Variation in Sympathetic Activity on Testicular Morphology in Immature Rats
- 24 April 2009
- journal article
- research article
- Published by Hindawi Limited in Andrologia
- Vol. 19 (4) , 448-451
- https://doi.org/10.1111/j.1439-0272.1987.tb02325.x
Abstract
In order to investigate the effect of increased and decreased sympathetic activity on testicular development, immature male rats were injected with isoproterenol or 6-hydroxydopamine form birth up to 49 days of age. Isoproterenol treatment resulted in a marked Leydig cell hypertrophy but the development of the spermatogenic epithelium was unaffected compared to that in saline treated controls. 6-hydroxydopamine treatment in a dose inhibiting the development of the parotid gland did not influence testicular development.Keywords
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