Immunological Impairment of Pregnancy in Mice by Lactate Dehydrogenase-X
- 1 August 1974
- journal article
- Published by Oxford University Press (OUP) in Biology of Reproduction
- Vol. 11 (1) , 108-115
- https://doi.org/10.1095/biolreprod11.1.108
Abstract
LDH-X, the sperm specific isozyme of lactate dehydrogenase was used as an antigen to induce infertility in female mice. Injection of rabbit anti-mouse LDH-X serum on Days 1-4 after coitus significantly reduced the number of pregnancies in these animals below the level observed in mice receiving serum from nonimmunized rabbits.Keywords
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