When Do Metal Complexes Protect the Biological System from Superoxide Toxicity and When Do They Enhance It?
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Free Radical Research Communications
- Vol. 1 (3) , 157-161
- https://doi.org/10.3109/10715768609083147
Abstract
Many copper and iron complexes can be reduced by O2- as well as by H2O2. According to the rates of reduction and the concentration of O2- and H2O2, the metal complexes may serve either as catalyst of O2- dismutation or as catalysts of the reaction between O2- and H2O2 to form OH. radical (Haber-Weiss reaction). Various factors which influence whether metal complexes protect the biological systems from superoxide toxicity or enhance it are discussed.Keywords
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