[Stimulation of pituitary LH and FSH secretion after immunoneutralization of endogenous substance P in the cycling rat].
- 28 March 1978
- journal article
- abstracts
- Vol. 286 (12) , 977-9
Abstract
In the cycling female Rat, administration of substance P antisera performed at noon on the proestrous day provokes a significant increase in LH and FSH serum level, right before or after the preovulatory surges, but had no effect on its occurrence or magnitude. These results suggest that substance P has a normal physiological inhibitory role in gonadotropin regulation.Keywords
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