A BrdU-enhanceable fragile site or viral modification site at 11q23.1 in lymphoblastoid cultures
- 1 January 1988
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 47 (4) , 201-203
- https://doi.org/10.1159/000132549
Abstract
Chromosomes prepared from EBV-transformed lymphoblastoid cell lines show an achromatic gap or fragile sitelike lesion at llq23.1. The low spontaneous expression of this lesion is greatly enhanced by BrdU and n-butyric acid. The lesion was expressed homozygously in all 16 cell lines examined. It is suggested that the lesion is a viral chromosome modification site.Keywords
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