TRANSMISSIBLE GASTROENTERITIS OF SWINE - INVITRO STABILITY OF THE CORONAVIRUS IN GASTRIC AND SMALL-INTESTINE JUICES

  • 1 January 1984
    • journal article
    • research article
    • Vol. 15  (3) , 359-364
Abstract
Low and high passaged cell culture strains of transmissible gastroenteririts (TGE) coronavirus were examined for stability in gastric and small intestine juices collected from 3-6 mo. old pigs killed at different times after last feeding. Results revealed high fragility of the TGE virus in these digestive liquids. Differences in stability were observed between strains of TGE virus. No correlation could be made between the level of stability and cell passage status of the virus strain. Thus, the stability of TGE coronavirus in gastric and small intestine juices can not be considered as a genetic marker of virulence. It will be necessary to take into account these data concerning fragility of TGE coronavirus for improvement of oral vaccination methods in pregnant sows using a live virus vaccine.

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