Finding the needle in the haystack. The dereplication of natural product extracts
- 30 June 1999
- journal article
- Published by Walter de Gruyter GmbH in Pure and Applied Chemistry
- Vol. 71 (6) , 1089-1094
- https://doi.org/10.1351/pac199971061089
Abstract
Dereplication is an integral part of the early stages of the drug discovery process, where there is a focus on the rapid identification of novel, biologically active metabolites from natural sources. We describe a strategy and a system for dereplication and offer several examples of its successful appplication.Keywords
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