A Chromatin-associated and Transcriptionally Inactive p53-Mdm2 Complex Occurs in mdm2 SNP309 Homozygous Cells
Open Access
- 1 July 2005
- journal article
- Published by Elsevier
- Vol. 280 (29) , 26776-26787
- https://doi.org/10.1074/jbc.m505203200
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in HumansCell, 2004
- MDM2 Is a Negative Regulator of p21 , Independent of p53Journal of Biological Chemistry, 2004
- Differential Activation of p53 by the Various Adducts of Mitomycin CJournal of Biological Chemistry, 2002
- Stress-Dependent Nucleolin Mobilization Mediated by p53-Nucleolin Complex FormationMolecular and Cellular Biology, 2002
- Mdm2 promotes the rapid degradation of p53Nature, 1997
- WAF1, a potential mediator of p53 tumor suppressionCell, 1993
- Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53Nature, 1993
- The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivationCell, 1992
- Mutations in the p53 gene occur in diverse human tumour typesNature, 1989
- Chromosome 17 Deletions and p53 Gene Mutations in Colorectal CarcinomasScience, 1989