Use of Chromium Chloride As the Coupling Agent in a Modified Plaque Assay Cells Producing Anti-Protein Antibody

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Abstract
Summary: A method is described for the detection and enumeration of mouse spleen cells producing antibody to protein antigens. The method employs chromium chloride as the coupling agent in a modified plaque technique and offers the advantages of greater economy, ease, speed and reproducibility over other available procedures.

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