Needle-tract seeding is a rare complication following percutaneous fine-needle biopsy of intra-abdominal tumours and only a few cases have been reported. Two cases of cutaneous implantation of a tumour in the needle-tract after biopsy of pancreatic carcinomas are presented. In experimental studies, seeding of malignant cells in the needle-tracts is common and the discrepancy between experimental and clinical findings is discussed.