Chemically modified electrodes for the electrocatalytic oxidation of nicotinamide coenzymes

1 January 1986

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Faraday Transactions 1: Physical Chemistry in Condensed Phases

Vol. 82 (4) , 1245-1258
https://doi.org/10.1039/f19868201245

Abstract

Methods for the oxidation of the cofactor, NADH, are discussed and the criteria for a successful mediator are set out. The kinetics of the system are analysed and linear free-energy relationships found for a number of different mediators. The variation of the reaction rate with pH is discussed. The successful oxidation of NADH using a modified electrode with Meldola's blue is described.

Keywords

MODIFIED ELECTRODE
NADH
NICOTINAMIDE
BLUE
MELDOLA'S
COFACTOR
COENZYMES
SUCCESSFUL