Catalysis of Ester Hydrolysis by Mixed Micelles ContainingN-α-Myristoyl-L-Histidine
- 2 June 1967
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 156 (3779) , 1243-1244
- https://doi.org/10.1126/science.156.3779.1243
Abstract
Model compounds are described for the study of the properties of amino acid side chains in the surface of micelles. Mixed micelles ofN-α-myristoyl-L-histidine and cetyltrimethylammonium bromide catalyze the hydrolyses ofp-nitrophenyl acetate andp-nitrophenyl caprylate at much higher rates than imidazole or histidine do. The reaction shows a kinetic behavior similar to that of surface-catalyzed reactions.This publication has 17 references indexed in Scilit:
- Synthetic Peptide Models of Enzyme Active Sites. III. Stereoselective Esterase Models1Journal of the American Chemical Society, 1966
- Organic Reactions Occurring in or on Micelles. III. Reaction of Methyl Bromide with Cyanide Ion1,2Journal of the American Chemical Society, 1965
- Structure and function of haemoglobinJournal of Molecular Biology, 1965
- Secondary Valence Force Catalysis. II. Kinetics of the Hydrolysis of Orthoesters and the Hydrolysis and Aminolysis of Carboxylic Esters in the Presence of Micelle-Forming Detergents1Journal of the American Chemical Society, 1965
- The Effect of Surfactants on Drug Stability I**Received August 21, 1959, from the School of Pharmacy, University of California Medical Center, San Francisco 22, Calif.Journal of the American Pharmaceutical Association (Scientific ed.), 1960
- Organic Reactions Occurring in or on Micelles. II. Kinetic and Thermodynamic Analysis of the Alkaline Fading of Triphenylmethane Dyes in the Presence of Detergent Salts1Journal of the American Chemical Society, 1959
- Organic Reactions Occurring in or on Micelles. I. Reaction Rate Studies of the Alkaline Fading of Triphenylmethane Dyes and Sulfonphthalein Indicators in the Presence of Detergent Salts1Journal of the American Chemical Society, 1959
- Non-enzymic reactions of acyl adenylate and imidazoleBiochimica et Biophysica Acta, 1957
- Imidazole Catalysis. I. The Catalysis of the Hydrolysis of Phenyl Acetates by ImidazoleJournal of the American Chemical Society, 1957
- The Imidazole-catalyzed Hydrolysis of p-Nitrophenyl Acetate1Journal of the American Chemical Society, 1957