Quantitative in Vitro Evaluation of the Energy Metabolism Influenced by Virginiamycin and Spiramycin used as Growth Promoters in Pig Nutrition

Publisher Website
Google Scholar
Abstract
Production rates of metabolites from a lactose diet were studied in vitro incubating stomach, ileal and cecal contents, collected from cannulated young pigs. Incubating stomach contents, bacterial activity was quantitatively not important after 4 hr of incubation. The bacterial activity in ileal contents on the other hand was characterized by an important production of lactic acid and volatile fatty acids. Addition of virginiamycin and spiramycin resulted in decreased organic acid production and in sparing of a measurable quantity of glucose. The fermentation of cecal contents was characterized by a pronounced volatile fatty acid fermentation, stimulated by spiramycin and decreased by virginiamycin. Bacterial production rates were also assessed by a dynamic incubation system to better imitate the intestinal transit. By combination with some in vivo data the sparing of carbohydrates with antibiotics could be expressed as a higher availability of the net energy content required for growth. The percentage calculated approximates the growth promoting ratio in vivo. Copyright © 1979. American Society of Animal Science . Copyright 1979 by American Society of Animal Science.