The prooligonucleotide approach IV : Synthesis of chimeric prooligonucleotides with 6 enzymolabile masking groups and unexpected desulfurization side reaction
- 1 February 1997
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 7 (3) , 263-268
- https://doi.org/10.1016/s0960-894x(96)00616-6
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- The prooligonucleotide approach. III: Synthesis and bioreversibility of a chimeric phosphorodithioate prooligonucleotideBioorganic & Medicinal Chemistry Letters, 1996
- The prooligonucleotide approach: II. Synthesis and stability studies of chimeric oligonucleotide modelsBioorganic & Medicinal Chemistry Letters, 1995
- The prooligonucleotide approach. I: Esterase-mediated reversibility of dithymidine S-alkyl-phosphorothiolates to dithymidine phosphorothioatesBioorganic & Medicinal Chemistry Letters, 1995
- Modified oligonucleotides as therapeutic and diagnostic agentsCurrent Opinion in Biotechnology, 1995
- Optimization of hybridizing abilities and nuclease resistance in the design of chimeric α-anomeric oligodeoxynucleotides containing β-anomeric gapsBioorganic & Medicinal Chemistry Letters, 1994
- Current concepts in antisense drug designJournal of Medicinal Chemistry, 1993
- The esterases: Perspectives and problemsChemico-Biological Interactions, 1993
- Hydrolysis of Carbonates, Thiocarbonates, Carbamates, and Carboxylic Esters of α-Naphthol, β-Naphthol, and p-Nitrophenol by Human, Rat, and Mouse Liver CarboxylesterasesPharmaceutical Research, 1993
- Increased specificity for antisense oligodeoxynucleotide targeting of RNA cleavage by RNase H using chimeric methylphosphonodiester/phosphodiester structuresNucleic Acids Research, 1992
- Antisense oligonucleotides: a new therapeutic principleChemical Reviews, 1990