Dissociation between Factor VIII (Activity and Antigen) and Ristocetin-Induced Platelet Aggregation in von Willebrand’s Disease

1 January 1975

journal article
Published by S. Karger AG in Acta Haematologica

Vol. 53 (1) , 44-48
https://doi.org/10.1159/000208154

Abstract

Previously we showed that von Willebrand patients could be separated into 2 groups on the basis of ristocetin-induced platelet aggregation and factor VII (antigen and activity). Ristocetin-induced platelet aggregation and factor VIII exhibited a positive correlation. This paper deals with 5 out of 31 examined von Willebrand patients in which ristocetin-induced platelet aggregation was not in correlation either with factor VIII activity or antigen. The importance of these findings is discussed.

Keywords

AGGREGATION
PLATELET
DISSOCIATION
ANTIGEN
FACTOR VIII
VON WILLEBRAND
RISTOCETIN

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