Comparison of the Structure of C- and N-Polyhedrins from Two Occluded Viruses Pathogenic for Orgyia pseudotsugata

Abstract
C- and N-polyhedrins from a cytoplasmic polyhedrosis virus (a double-stranded RNA virus) and a nuclear polyhedrosis virus (a DNA virus), respectively, of O. pseudotsugata were compared. Although both polyhedrins appear to stabilize their respective virions and have similar MW, they differed in amino acid composition, tryptic peptide elution profiles from a cation-exchange resin and N-terminal amino acid sequence and showed no antigenic relatedness. These 2 proteins probably originated independently of each other.