Ceramide binds to the CaLB domain of cytosolic phospholipase A2and facilitates its membrane docking and arachidonic acid release
Open Access
- 9 November 2000
- journal article
- fj express-summary
- Published by Wiley in The FASEB Journal
- Vol. 15 (1) , 7-9
- https://doi.org/10.1096/fj.00-0370fje
Abstract
Excessive production of eicosanoids is characteristic of many inflammatory diseases. In this study we show that ceramide, which is an early messenger of inflammatory cytokine action, exerts a dual ef...Keywords
Funding Information
- Deutsche Forschungsgemeinschaft (HU-842/2-2)
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