Genetic control of susceptibility to experimental allergic neuritis and the immune response to P 2 protein
- 1 August 1981
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 31 (8) , 950
- https://doi.org/10.1212/wnl.31.8.950
Abstract
Genetic control of susceptibility to experimental allergic neuritis (EAN) was investigated in three rat strains. EAN expression is high in the Lewis rat and low in the Brown Norwegian and Sprague-Dawley rat strains. The capacity to mount a significant cell-mediated response to the P, protein or peripheral nerve was associated with genetic susceptibility to EAN. Failure to mount a significant immune response to P, may be a critical factor in controlling expression of the disease.This publication has 6 references indexed in Scilit:
- Experimental allergic neuritis. I. Rat strain differences in the response to bovine myelin antigensBrain Research, 1980
- Experimental Allergic Neuritis in the Lewis RatJournal of Neuropathology and Experimental Neurology, 1979
- Experimental Allergic Neuritis Induced by Sensitization with GalactocerebrosideScience, 1979
- HLA typing and Guillain‐Barré syndromeNeurology, 1979
- Experimental allergic neuritis induced by a basic neuritogenic protein (P1 L) of human peripheral nerve originEuropean Journal of Immunology, 1977
- Allergic Neuritis Induced in Rats Without the Use of Mycobacteria.Experimental Biology and Medicine, 1963